Memory Consolidation: How Stress Develops After Exposure To A Traumatic Event And What Can Be Done to Reduce It

Within a 72-hour time window of the event: 20+ minutes game play

Prefaced by recall of disturbing images from the event

Maximizing visuospatial interactions

Result: preventing intrusive memories of the event

free prevention app: mobile browser version

In the hours immediately following exposure to a traumatic event, memory consolidation, including imagery and associated emotional learning occurs. These can harden into intrusive memories, primarily images, but also as smells, sounds, other sensations, that later progress and trigger distress. On a continuum, subsequent distress ranges from mild but upsetting levels, through “subthreshold posttraumatic stress disorder” features affecting social/work spheres and suicidality (Zlotnick et al., 2002) all the way to full-blown acute and posttraumatic stress disorders.

A growing body of research (James et al., 2015; Kessler et al., 2018; Kessler et al., 2019a; Kessler et al., 2019b; Iyadurai et al., 2019; Kanstrup et al., 2021; Thorarinsdottir et al. 2022; Singh et al., 2022) is showing that targeting and preventing the early formation of intrusive memories immediately after exposure to a traumatic event, using principles derived from memory consolidation studies, can significantly reduce distress and its progression, “nipping it in the bud.”

(1) 20+ minutes of interacting with an online animation (for example, game play) (2) including visuospatial exercises (visualizing pieces in one’s mind as preparation for moving them where needed by game rules, then executing the movement), (3) within a time window of 72 hours or less, (4) targeting event hotspots (Gray & Holmes, 2008), can (5) reduce intrusive memories of disturbing imagery.

As mentioned above, this approach targets a critical element, intrusive memories, implicated in subsequent development of disturbing levels of stress following exposure to a traumatic event. Most often experienced as images, these can also be sounds, smells, other triggering sensations. Intrusive memories can be experienced within current reality: they intrude as recall of a past, not current event. A subset of intrusive memories, flashbacks, dissociative experiences during which the person feels like they are reliving the events at the time they occurred, can blur this past-present time distinction.

A game like Tetris is often used in these research studies and includes the needed visuospatial animation exercises. Before engaging in the game play, a critical element is for the user to recall hotspots, disturbing images from the event. They are instructed to focus on the mental movement of game pieces (mind’s eye perspective), a critically necessary component. Then, play for a minimum of 10 minutes, plus additional game play totaling 20+ minutes, within the 72-hour time window. Booster sessions following the same protocol while optional (Kanstrup et al., 2021), in our opinion are useful: in our adaptation of the protocol, the “+” in “20+ minutes”.

A variety of game animations featuring visuospatial-based interaction, including explicit instructions to visually rehearse then move pieces, can be used since the goal is for the user to experience the type of interactions, including visuospatial movement, which have been shown to prevent subsequent intrusive memories.

Based on research testing game animations that do not produce positive results consistent with recent research (James et al., 2015; Asselbergs et al., 2018), we hypothesize that their design may not sufficiently draw user-attention to the visuospatial component. This must be explicit in the instructions delivered to users (Singh, 2022). “Critically [emphasis added], participants were asked to ‘try to work out in your mind’s eye where best to place and rotate these [Tetris] blocks in order to make as many complete horizontal lines as you can and get the best score’ (Lau-Zhu et al., 2017). “The emphasis on mental rotation is key to ensure that the visuospatial demand of Tetris gameplay is maximised, as greater visuospatial demand has been associated with fewer subsequent intrusive memories…” (Kanstrup et al., 2020).

Concurrently (1) seeing the next game piece to encourage next-move planning/visualization, (2) encouraging angled play (see images and video below) incentivized by doubling a successful shot’s point score when angled play is used, (3) viewing a timer bar timing-out the current screen, (4) adding options for bilateral eye movement and sound and (5) achieving high overall scores all serve to split the user’s attention and increase visuospatial demand.*

Another type of research result similarly demonstrated less frequency of intrusive memories but not reduced intensity. This research design using Tetris raised the question whether reducing the frequency of intrusive memories, which was demonstrated in this and other studies, is as helpful as reducing their intensity. Intensity, not measured in other studies, was measured in this study and did not occur. The research study’s authors also noted study limitations including differences between their sample population, who were exposed to a trauma film (see James, et al., 2016), and sample populations in other studies who had been exposed to real-life trauma events (Badawi, et al., 2022).

A research study done to determine if “proactive” playing of a game animation, prior to exposure to a trauma event (film), is helpful reported the following: there were no differences in intrusive memory frequencies between a control group and the group using the intervention (James et al., 2016b). It appears that cognitive inoculation prior to event exposure does not produce positive results.

While there is emerging research evidence for the efficacy of the approach delivered in the time-window following an event, that includes explicit attention by subjects to visuospatial visualization and manipulation , researchers often qualify results with the need for more research in order to conclusively demonstrate usefulness, as well as better determine which features need to be included/maximized to achieve the best results.

With this in mind, as well as the adage ‘the perfect need not be the enemy of the good,’ plus the overall safety of these strategies (following safe-use protocols), we have made these game animations available to potential users who are encouraged to weigh the pro’s and con’s of utilizing them.

A game animation that we created to maximize experiencing the 5 key elements (see above*) is available for free and paid memberships and can be self-administered following our adapted protocol. It’s active ingredients can be distilled down to high visuospatial demand increased by a user’s motivation to get the highest possible score in the shortest time or before added obstacles end the game.

Options include timers (blue bar) to advance the screen if a choice is not timely and optional audiovisual distractors to strengthen a key memory consolidation-blocking element: split-attention (see images below).

angled play, earning double scoring, to improve visuospatial effects

“thumbs up” double score for successful angled play

angled play video

After the 72-hour event-exposure time window (the time during which memory consolidation occurs), disturbing effects of acute or posttraumatic stress, if experienced, can be reduced through activating memory reconsolidation.

References

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